Thursday June 3, 15:03

Research: Vaccine against breast cancer

The researchers evaluated the vaccine first in a transgenic mouse that spontaneously developed mammary tumors and in mice that received transplants of mammary tumors

The announcement of the discovery of a vaccine against breast cancer in mice published in the latest issue of "Medicine" raises logically, many hopes.

Especially that about 12 million new cases of breast cancers are detected, currently, each year worldwide, causing 20,000 deaths per day.

So obviously, such a vaccine is more than expected. But two-thirds of animal tests is not accepted as a possible treatments for humans. Is it in this case figure? It is impossible to say today.

In practice, the vaccine against breast cancer developed by the team of Professor Vincent Tuohy (Lerner Research Institute and University in Cleveland, Ohio) targeting the alpha-lactalbumin, a protein specific differentiation of the breast, expressed in the majority of breast cancers and, outside of cancer, only during lactation.

It provides protection in mice free of the disease and is treated in mice with tumors. The researchers evaluated the vaccine first in a transgenic mouse that spontaneously developed mammary tumors and in mice that received transplants of mammary tumors.

The results are encouraging. Prophylactic vaccination of genetically modified mice completely protects from breast cancer (when cancer is observed in all mice in the control group receiving only the adjuvant). The vaccine injected into other mice, two weeks before transplantation of mammary tumors, also inhibits tumor growth.

In addition, the vaccine does not cause adverse immune reactions. "Immunization with alpha-lactalbumin could give a safe and effective protection against developing breast cancer for women who are too old to have children," conclude the researchers who believe that breast cancer can be prevented completely. But we must not forget that women are not mice!

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Research: Vaccine against breast cancer

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